When it comes to art the know saying “size does not matter” is usually correct.
While most bed rooms are designed in a rather space efficient manner, A large art piece could make the room feel bigger and more spacious.
As mentioned before, Make sure to leave enough white space around the artwork.
Without enough space around it, The artwork will not stand out and get the visual focus it deserves.
In the case of a master bedroom we fill like a big work of art is a better fit than a collage of small artworks.